Creatinine Clearance (Cockcroft–Gault)

Excel Formulas › Healthcare & Medical

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Estimate kidney function with the Cockcroft–Gault equation — a weight-, age-, and creatinine-based estimate of creatinine clearance, with a sex adjustment. A classic clinical formula.


Quick formula: creatinine clearance (mL/min):
=(140 - age) * kg / (72 * serum_creatinine) * sex_factor
The Cockcroft–Gault estimate; multiply by 0.85 for females.

The example

Age 60, 70 kg, SCr 1.0.

AB
1ItemValue
2(140−60)×70—
3÷ (72×1.0)→ ~78 mL/min

The formula

The formula:

=(140 - age) * kg / (72 * scr) * sex // Cockcroft–Gault

How it works

How it works:

  1. (140 - age) × weight_kg / (72 × serum_creatinine) is the base estimate in mL/min.
  2. Multiply by 0.85 for females (the sex factor); use 1 for males.
  3. Serum creatinine is in mg/dL for this version of the equation.
  4. Lower clearance indicates reduced kidney function — often used to adjust drug dosing.

Educational use only. These are general Excel formulas for learning spreadsheet techniques — not medical advice or a substitute for clinical judgment, professional guidelines, or verified dosing references. Always confirm calculations against authoritative sources and institutional protocols.

Try it: interactive demo

Live demo

Age, weight (kg), SCr (mg/dL), sex.

CrCl:

Variations

Female adjustment

× 0.85:

=base_crcl * 0.85

Male (no adjust)

Factor of 1:

=(140 - age) * kg / (72 * scr)

Category lookup

Band the result:

=LOOKUP(crcl, {0;30;60;90}, {"Severe";"Moderate";"Mild";"Normal"})

Pitfalls & errors

Sex factor. Multiply by 0.85 for females; 1 for males.

Creatinine units. This form uses mg/dL — a different constant applies for µmol/L.

Estimate only. Weight choice (actual vs ideal) and edge cases affect accuracy.

Practice workbook

📊
Download the free Creatinine Clearance (Cockcroft–Gault) practice workbook
A creatinine-clearance sheet with the female, male, and category variants, plus 4 challenges with answers. No sign-up required.

Frequently asked questions

How do I calculate creatinine clearance in Excel?
Use Cockcroft–Gault: =(140 - age) * kg / (72 * serum_creatinine), then multiply by 0.85 for females.
What's the sex factor?
Multiply by 0.85 for females; use 1 for males.
What units does this use?
Weight in kg and serum creatinine in mg/dL; the result is mL/min.

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